Cell Death Activator CIDE-B (CIDE B) Antibody

Este producto es parte de CIDEB - Cell death-inducing DFFA-like effector b
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357.5€ (100 µg)

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935106861
info@markelab.com
name
Cell Death Activator CIDE-B (CIDE B) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx038240
tested applications
ELISA, WB

Description

Rabbit Polyclonal against the CIDE B protein.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Cell Death Activator CIDE-B (CIDE B)
Host
Rabbit
Reactivity
Human
Recommended Dilution
ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by Protein A/G column chromatography.
Size 1
100 µg
Size 2
1 mg
Form
Lyophilized
Tested Applications
ELISA, WB
Buffer
Prior to lyophilization: 0.02% NaN3.
Availability
Shipped within 7-15 working days.
Storage
Store at -20 °C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
NCBI Accession
NM_014430
Alias
CIDEB, cell death-inducing DFFA-like effector b, cell death inducing DFFA like effector b,CIDE-B
Background
Antibody anti-CIDEB
Status
RUO
Note
Concentration: Lyophilized form: Not applicable.  After reconstitution: 1 mg/ml. - 

Descripción

CIDEB is a protein critical for lipid metabolism and apoptosis, primarily expressed in the liver and associated with lipid droplet formation and triglyceride metabolism. It regulates lipid droplet growth and lipoprotein secretion, influencing hepatic lipid storage and export. CIDEB also participates in apoptosis by promoting the activation of caspase-dependent pathways, contributing to programmed cell death under stress conditions. Dysregulation of CIDEB has been implicated in liver diseases such as steatosis, non-alcoholic fatty liver disease (NAFLD), and liver fibrosis. Targeting CIDEB-mediated pathways is being explored for the treatment of metabolic liver diseases and conditions associated with altered lipid metabolism.

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