Cell Death Activator CIDE-B (CIDE B) Antibody
357.5€ (100 µg)
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935106861
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name
Cell Death Activator CIDE-B (CIDE B) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx038240
tested applications
ELISA, WB
Description
Rabbit Polyclonal against the CIDE B protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Cell Death Activator CIDE-B (CIDE B) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by Protein A/G column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB |
| Buffer | Prior to lyophilization: 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | NM_014430 |
| Alias | CIDEB, cell death-inducing DFFA-like effector b, cell death inducing DFFA like effector b,CIDE-B |
| Background | Antibody anti-CIDEB |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
CIDEB is a protein critical for lipid metabolism and apoptosis, primarily expressed in the liver and associated with lipid droplet formation and triglyceride metabolism. It regulates lipid droplet growth and lipoprotein secretion, influencing hepatic lipid storage and export. CIDEB also participates in apoptosis by promoting the activation of caspase-dependent pathways, contributing to programmed cell death under stress conditions. Dysregulation of CIDEB has been implicated in liver diseases such as steatosis, non-alcoholic fatty liver disease (NAFLD), and liver fibrosis. Targeting CIDEB-mediated pathways is being explored for the treatment of metabolic liver diseases and conditions associated with altered lipid metabolism.
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