CD16 Antibody (FITC)
364€ (100 tests)
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Name
CD16 Antibody (FITC)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx139440
Tested Applications
FCM
Description
CD16 Antibody is a Mouse Monoclonal against CD16.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: CD16 Immunogen: Human neutrophils. |
| Host | Mouse |
| Reactivity | Human, Monkey |
| Detection Method | Laser Line: 488 Excitation/Emission: 499/515 |
| Recommended Dilution | FCM: 4 µl/100 µl of whole blood or 106 cells. Validated in IHC-F. Optimal dilutions/concentrations should be determined by the end user.The content of a vial (0.4 ml) is sufficient for 100 tests. |
| Clonality | Monoclonal |
| Conjugation | FITC |
| Isotype | IgG1 Kappa |
| Clone ID | C307 |
| Size 1 | 100 tests |
| Tested Applications | FCM |
| Buffer | Stabilizing PBS solution containing 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P08637 |
| Gene ID | 2214 |
| Alias | CD16,FCG3,CD16A,FCGR3,IGFR3,IMD20,FCR-10,FCRIII,CD16-II,FCGRIII,FCRIIIA,FcGRIIIA,Low affinity immunoglobulin gamma Fc region receptor III-A,IgG Fc receptor III-A,IgG Fc receptor III-2 |
| Background | Antibody anti-FCGR3A |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
FCGR3A, or Fc gamma receptor IIIa, is a membrane-bound protein that plays a crucial role in the immune system, specifically in mediating immune responses through the recognition of the Fc region of IgG antibodies. This receptor is primarily expressed on the surface of natural killer (NK) cells, macrophages, monocytes, and dendritic cells, where it facilitates antibody-dependent cellular cytotoxicity (ADCC) and other immune responses. It is part of the broader family of Fc gamma receptors (FcγRs), which are responsible for binding to the Fc region of IgG antibodies, thereby linking humoral and cellular immunity. FCGR3A has garnered considerable attention in immunology due to its role in recognizing and responding to immune complexes, infected cells, and tumor cells coated with IgG antibodies. Variations in the gene encoding FCGR3A have been implicated in differential responses to infections, autoimmune diseases, and cancer therapies
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