Calcium-Transporting ATPase Type 2C Member 1 (ATP2C1) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
ATP2C1 Antibody is a Rabbit Polyclonal Antibody against ATP2C1.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Calcium-Transporting ATPase Type 2C Member 1 (ATP2C1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | IHC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P98194 |
| Gene ID | 27032 |
| NCBI Accession | NP_001186114.1 |
| Background | Antibody anti-ATP2C1 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
Related Products
ATP2C1 antibody
The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium ions. Defects in this gene cause Hailey-Hailey disease, an autosomal dominant disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.
Ver Producto
Calcium-Transporting ATPase Type 2C Member 1 (ATP2C1) Antibody
ATP2C1 Antibody is a Rabbit Polyclonal Antibody against ATP2C1.
Ver Producto
Calcium-Transporting ATPase Type 2C Member 1 (ATP2C1) Antibody
ATP2C1, also known as PMR1, it belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the calcium. The human homologue, ATP2C1 (also designated SPLA in rat), also regulates the transport of calcium in the Golgi complex and is related to other P-type ATPases family members, such as the sarco (endo)plasmic calcium ATPase (SERCA) and the plasma membrane calcium ATPase (PCMA). ATP2C1 is a transmembrane protein that exists as two splice variants, which vary by 20 amino acids. Defects in ATP2C1 cause Hailey-Hailey disease, which is an autosomal dominant disorder that is characterized by blisters and erosions of the skin. These findings provide further evidence that PMR1 plays a key role in maintaining the integrity of the epidermis by controlling intracellular calcium signaling.
Ver Producto