DDB1- and CUL4-Associated Factor 16 (DCAF16) Antibody
357.5€ (100 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
DDB1- and CUL4-Associated Factor 16 (DCAF16) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx146389
tested applications
ELISA, WB, IHC
Description
DDB1- and CUL4-Associated Factor 16 (DCAF16) Antibody is a Rabbit Polyclonal against DDB1- and CUL4-Associated Factor 16 (DCAF16).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | DDB1- and CUL4-Associated Factor 16 (DCAF16) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9NXF7 |
| Gene ID | 54876 |
| NCBI Accession | BC050697 |
| Alias | C4orf30 |
| Background | Antibody anti-DCAF16 |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
DDB1 and CUL4 associated factor 16 (DCAF16) is a member of the WD40-repeat-containing family of proteins that functions as a substrate receptor in the CUL4-DDB1 E3 ubiquitin ligase complex. DCAF16 is involved in mediating the ubiquitination of nuclear and cytoplasmic substrates, ensuring proper protein turnover and cellular homeostasis. It has been implicated in nuclear-cytoplasmic transport processes and may influence the stability of proteins involved in transcriptional regulation and signal transduction. While its specific biological roles are still under investigation, DCAF16 is thought to play a role in the regulation of cellular stress responses and developmental processes. Its expression is widespread, and its functionality within the ubiquitin-proteasome system indicates a critical role in maintaining protein quality control and supporting adaptive cellular responses. Further research is required to define its substrate profile and to better understand its contributions to cellular function and disease.
Related Products
DDB1- and CUL4-Associated Factor 16 (DCAF16) Antibody
DDB1- and CUL4-Associated Factor 16 (DCAF16) Antibody is a Rabbit Polyclonal against DDB1- and CUL4-Associated Factor 16 (DCAF16).
Ver Producto
Human DDB1- and CUL4-associated factor 16 (DCAF16) ELISA Kit
Human DDB1- and CUL4-associated factor 16 (DCAF16) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human DDB1- and CUL4-associated factor 16 (DCAF16) concentrations in tissue homogenates, cell lysates and other biological fluids.
Ver Producto