Tyrosine-Protein Kinase Mer (MERTK) Antibody

Este producto es parte de MERTK - MER proto-oncogene, tyrosine kinase
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260€ (50 µl)

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935106861
info@markelab.com
name
Tyrosine-Protein Kinase Mer (MERTK) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx214454
tested applications
ELISA, IHC

Description

MERTK Antibody is a Rabbit Polyclonal against MERTK.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetTyrosine-Protein Kinase Mer (MERTK)
HostRabbit
ReactivityHuman, Mouse, Rat
Recommended DilutionELISA: 1/1000 - 1/5000, IHC: 1/25 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationUnconjugated
IsotypeIgG
PurificationAntigen Affinity Chromatography.
Size 150 µl
Size 2100 µl
FormLiquid
Tested ApplicationsELISA, IHC
BufferPBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol.
AvailabilityShipped within 5-10 working days.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDQ12866
Gene ID10461
NCBI AccessionNP_006334.2
OMIM604705
AliasMER,RP38,c-Eyk,c-mer,Tyro12,Receptor tyrosine kinase MerTK,Proto-oncogene c-Mer
BackgroundAntibody anti-MERTK
StatusRUO

Descripción

MERTK (MER Proto-Oncogene, Tyrosine Kinase) is a member of the TAM (TYRO3, AXL, and MERTK) receptor tyrosine kinase family, which plays a crucial role in the regulation of immune response, cell survival, migration, and phagocytosis. This gene was identified due to its homology with the avian oncogene v-Mer and is involved in the clearance of apoptotic cells and immune tolerance. The MERTK protein is primarily expressed in macrophages, dendritic cells, and retinal pigment epithelial cells. Dysregulation of MERTK has been implicated in various diseases, including cancer, autoimmune disorders, and retinal degenerative diseases.
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