Bovine F11R (Junctional adhesion molecule A) ELISA Kit

Este producto es parte de F11R - F11 receptor
Bovine F11R (Junctional adhesion molecule A) ELISA Kit
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Name
Bovine F11R (Junctional adhesion molecule A) ELISA Kit
Category
ELISA Kits
Provider
FineTest
Reference
EB0041
Tested Applications
ELISA

Documentos del producto

Instrucciones
Descargar
Data sheet

Especificaciones del producto

Category
ELISA Kits
Reactivity
Bovine
Detection Method
Colorimetric
Assay Data
4 hours
Assay Type
Sandwich ELISA, Double Antibody
Test Range
0.156-10ng/ml
Sensitivity
0.094ng/ml
Size 1
96T
Tested Applications
ELISA
Sample Type
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 12 months
UniProt ID
Q9XT56
Alias
Junctional adhesion molecule A,JAM,KAT,JAM1,JAMA,JCAM,CD321,PAM-1,Junctional adhesion molecule 1,Platelet F11 receptor
Background
Elisa kits for F11R
Status
RUO

Background

The F11 receptor (F11R), also known as Junctional Adhesion Molecule-A (JAM-A), is an integral protein involved in cell-cell adhesion, particularly in the tight junctions of epithelial and endothelial cells. It belongs to the immunoglobulin superfamily and is vital for maintaining barrier integrity in tissues where selective permeability is essential, such as blood-brain, blood-testis, and blood-retina barriers. F11R plays a key role in regulating paracellular permeability, leukocyte transmigration, and cellular signaling, supporting immune responses, hemostasis, and wound healing. It also mediates interactions between platelets, contributing to thrombus formation and platelet aggregation. Expressed in a variety of tissues, including the endothelium, epithelium, and on platelets, F11R facilitates cell adhesion and communication in multiple physiological processes. Notably, it has been implicated in pathological conditions like inflammation, atherosclerosis, and cancer metastasis, where its dysregulation disrupts cellular integrity and promotes disease progression.

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