Biotin Gastrin Releasing Peptide (Biotin)
312€ (1 mg)
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Name
Biotin Gastrin Releasing Peptide (Biotin)
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx265302
Description
Biotin - Gastrin Releasing Peptide (Biotin) is a peptide.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | Biotin Gastrin Releasing Peptide |
| Origin | Human |
| Conjugation | Biotin |
| Observed MW | 3085.74 Da |
| Purity | > 95% (HPLC) |
| Size 1 | 1 mg |
| Size 2 | 5 mg |
| Size 3 | 10 mg |
| Form | Lyophilized |
| Buffer | Not applicable. |
| Availability | Shipped within 10-20 working days. |
| Storage | Store dry at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | BN,GRP-10,proGRP,preproGRP |
| Background | Protein GRP |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
GRP is a neuropeptide that acts as the mammalian equivalent of bombesin, a peptide involved in stimulating the release of gastrin and other gastrointestinal hormones GRP is primarily secreted by nerve endings in the gastrointestinal tract and pancreas, where it regulates gastric acid secretion, gastrointestinal motility, and nutrient absorption It exerts its effects by binding to the gastrin-releasing peptide receptor (GRPR), a G-protein-coupled receptor GRP plays an important role in cell proliferation, wound healing, and neural signaling in the central nervous system Dysregulated GRP expression is associated with the pathogenesis of cancers, particularly small cell lung cancer (SCLC) and prostate cancer, where it promotes tumor cell growth and metastasis GRP and its receptor are also implicated in inflammatory processes and neurological conditions, making them potential targets for cancer therapy and gastrointestinal disorders
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