Beta-Centractin (ACTR1B) Antibody
364€ (100 µg)
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935106861
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name
Beta-Centractin (ACTR1B) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx230126
tested applications
ELISA, WB, IHC, IF/ICC
Description
ACTR1B Antibody is a Rabbit Polyclonal against ACTR1B.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Beta-Centractin (ACTR1B) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/200 - 1/2000, IHC: 1/20 - 1/200, IF/ICC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P42025 |
| Gene ID | 10120 |
| OMIM | 605144 |
| Alias | ACTR1B,ARP1B,CTRN2,PC3,centractin beta |
| Background | Antibody anti-ACTR1B |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
ACTR1B is a paralog of ACTR1A and similarly functions as part of the dynactin complex. It stabilizes the interaction between dynein motors and cargo for efficient intracellular transport. Structurally, ACTR1B forms filament-like structures with other dynactin components, closely resembling actin polymers. Its expression is critical for endosomal and lysosomal trafficking, mitotic spindle positioning, and nuclear migration. ACTR1B dysfunction can lead to disruptions in cellular organization and neurological development, underscoring its importance in cytoskeletal dynamics.
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