Beta-Centractin (ACTR1B) Antibody
637€ (100 µl)
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Name
Beta-Centractin (ACTR1B) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx111064
Tested Applications
ELISA, IHC, IF/ICC
Description
Arp1 Actin-Related Protein 1 Homolog B, Centractin Beta (Yeast) Antibody is a Rabbit Polyclonal antibody against Arp1 Actin-Related Protein 1 Homolog B, Centractin Beta (Yeast).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Beta-Centractin (ACTR1B) Immunogen: Human ACTR1B. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, IHC, IF/ICC |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P42025 |
| Gene ID | 10120 |
| OMIM | 605144 |
| Alias | ACTR1B,ARP1B,CTRN2,PC3,centractin beta |
| Background | Antibody anti-ACTR1B |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ACTR1B is a paralog of ACTR1A and similarly functions as part of the dynactin complex. It stabilizes the interaction between dynein motors and cargo for efficient intracellular transport. Structurally, ACTR1B forms filament-like structures with other dynactin components, closely resembling actin polymers. Its expression is critical for endosomal and lysosomal trafficking, mitotic spindle positioning, and nuclear migration. ACTR1B dysfunction can lead to disruptions in cellular organization and neurological development, underscoring its importance in cytoskeletal dynamics.
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