Beta-1,3-Galactosyl-O-Glycosyl-Glycoprotein Beta-1,6-N-Acetylglucosaminyltransferase 7 (GCNT7) Antibody

292.5€ (80 µl)
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935106861
info@markelab.com
name
Beta-1,3-Galactosyl-O-Glycosyl-Glycoprotein Beta-1,6-N-Acetylglucosaminyltransferase 7 (GCNT7) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx030450
tested applications
ELISA, WB
Description
GCNT7 is a glycosyltransferase (By similarity).
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Beta-1,3-Galactosyl-O-Glycosyl-Glycoprotein Beta-1,6-N-Acetylglucosaminyltransferase 7 (GCNT7) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified through a protein A column, followed by peptide affinity purification. |
Size 1 | 80 µl |
Size 2 | 400 µl |
Form | Liquid |
Tested Applications | ELISA, WB |
Buffer | PBS containing 0.09% sodium azide. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q6ZNI0 |
Alias | GCNT7, C20orf106 |
Background | Antibody anti-GCNT7 |
Status | RUO |
Descripción
Glucosaminyl (N-acetyl) transferase 7 (GCNT7) is a member of the glycosyltransferase family involved in the synthesis of branched O-glycans, which regulate glycoprotein structure and function GCNT7’s enzymatic activity is critical for forming complex glycan structures that mediate cell-cell communication, adhesion, and immune responses It is primarily expressed in specific epithelial tissues, although its functional roles are still being explored Studies suggest GCNT7 participates in epithelial barrier maintenance and mucin production, which are essential for protecting mucosal surfaces from pathogens Dysregulation of GCNT7 has been associated with certain cancers, where its altered activity disrupts normal glycosylation, contributing to tumor growth, invasion, and immune evasion Additionally, GCNT7 may play a role in embryonic development and cellular differentiation by modulating glycoprotein biosynthesis Emerging evidence indicates its relevance in glycan-mediated signaling pathways and potential as a target for studying epithelial and cancer biology
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