BAI3-Specific Antibody

Este producto es parte de ADGRB - Adhesion G protein-coupled receptor B
Product Graph
364€ (100 µg)

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935106861
info@markelab.com
name
BAI3-Specific Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx230792
tested applications
ELISA, WB

Description

BAI3-Specific Antibody is a Rabbit Polyclonal against BAI3-Specific.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
BAI3-Specific
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purity
≥ 95% (SDS-PAGE)
Purification
Purified by immunogen affinity chromatography.
Size 1
100 µg
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Availability
Shipped within 5-12 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
O60242
Gene ID
577
Alias
ADGRB3,BAI3
Background
Antibody anti-ADGRB3
Status
RUO
Note
Concentration: 2 mg/ml - Validity: 12 months.

Descripción

ADGRB3, known as BAI3, is a GPCR highly expressed in the brain, where it regulates synaptic development and neuronal connectivity. It plays a role in dendritic arborization and synapse formation, supporting neuronal circuitry and communication. ADGRB3 interacts with proteins involved in synaptic organization and phagocytosis, contributing to the removal of apoptotic neurons and cellular debris. Dysregulation of ADGRB3 has been associated with autism spectrum disorders and other neurodevelopmental conditions due to its role in synaptic refinement. Additionally, it is implicated in vascular homeostasis, although its angiogenic functions are less defined compared to ADGRB1. ADGRB3’s dual involvement in synaptic and vascular processes highlights its importance in neurovascular coupling and overall brain health.

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