B-Cell Antigen Receptor Complex-Associated Protein Beta Chain (CD79B) Antibody
292.5€ (80 µl)
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935106861
info@markelab.com
name
B-Cell Antigen Receptor Complex-Associated Protein Beta Chain (CD79B) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx028989
tested applications
ELISA, WB
Description
The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-beta protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | B-Cell Antigen Receptor Complex-Associated Protein Beta Chain (CD79B) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P40259 |
| Alias | B29,IGB,AGM6,Igbeta,B-cell-specific glycoprotein B29,Ig-beta,Immunoglobulin-associated B29 protein,B-cell antigen receptor complex-associated protein beta chain |
| Background | Antibody anti-CD79B |
| Status | RUO |
Descripción
CD79B, also known as Ig-beta, is a protein encoded by the CD79B gene in humans. It is an integral component of the B cell receptor (BCR) complex, which is crucial for B cell development, activation, and function. The BCR complex consists of membrane-bound immunoglobulin (Ig) molecules associated with the CD79A (Ig-alpha) and CD79B (Ig-beta) heterodimer. This complex plays a pivotal role in the immune system by recognizing specific antigens, initiating signaling cascades that lead to B cell activation, proliferation, and differentiation. The importance of CD79B in immune responses and its implications in various clinical conditions make it a significant focus of immunological research.
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