B-Cell Antigen Receptor Complex-Associated Protein Beta Chain (CD79B) Antibody
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935106861
info@markelab.com
Precio
250€ (80 µl)
Antibody anti-CD79B
proveedor
Abbexareference
abx028989Tested Applications
ELISA, WBreactivity
Human, Mousestatus
RUOclonality
PolyclonalDescripción
The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-beta protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described.
Background
CD79B, also known as Ig-beta, is a protein encoded by the CD79B gene in humans. It is an integral component of the B cell receptor (BCR) complex, which is crucial for B cell development, activation, and function. The BCR complex consists of membrane-bound immunoglobulin (Ig) molecules associated with the CD79A (Ig-alpha) and CD79B (Ig-beta) heterodimer. This complex plays a pivotal role in the immune system by recognizing specific antigens, initiating signaling cascades that lead to B cell activation, proliferation, and differentiation. The importance of CD79B in immune responses and its implications in various clinical conditions make it a significant focus of immunological research.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human, Mouse
immunogen target
B-Cell Antigen Receptor Complex-Associated Protein Beta Chain (CD79B)
host
Rabbit
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB
purification
Purified through a protein A column, followed by peptide affinity purification.
buffer
PBS containing 0.09% sodium azide.
size 1
80 µl
size 2
400 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
CD79B
dry ice
No
availability
Shipped within 5-10 working days.
alias
B29,IGB,AGM6,Igbeta,B-cell-specific glycoprotein B29,Ig-beta,Immunoglobulin-associated B29 protein,B-cell antigen receptor complex-associated protein beta chain
uniprot id
note
This product is for research use only.
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