B-Cell Antigen Receptor Complex-Associated Protein Beta Chain (CD79B) Antibody

Este producto es parte de CD79B molecule
B-Cell Antigen Receptor Complex-Associated Protein Beta Chain (CD79B) Antibody
195€ (20 µl)

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Name
B-Cell Antigen Receptor Complex-Associated Protein Beta Chain (CD79B) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx001650
Tested Applications
ELISA, WB, IHC

Description

CD79B Antibody is a Rabbit Polyclonal antibody against CD79B. The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-beta protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
Target: B-Cell Antigen Receptor Complex-Associated Protein Beta Chain (CD79B)
Immunogen: Synthetic peptide corresponding to CD79B. The exact sequence is proprietary.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Assay Type
Concentration: > 0.2 mg/ml
Recommended Dilution
ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
Calculated MW: 26 kDa  Observed MW: 36 kDa
Purification
Purified by affinity chromatography.
Size 1
20 µl
Size 2
100 µl
Size 3
2 × 100 µl
Form
Liquid
Tested Applications
ELISA, WB, IHC
Buffer
PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P40259
Gene ID
974
NCBI Accession
NP_000617.1
Alias
B29,IGB,AGM6,Igbeta,B-cell-specific glycoprotein B29,Ig-beta,Immunoglobulin-associated B29 protein,B-cell antigen receptor complex-associated protein beta chain
Background
Antibody anti-CD79B
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Background

CD79B, also known as Ig-beta, is a protein encoded by the CD79B gene in humans. It is an integral component of the B cell receptor (BCR) complex, which is crucial for B cell development, activation, and function. The BCR complex consists of membrane-bound immunoglobulin (Ig) molecules associated with the CD79A (Ig-alpha) and CD79B (Ig-beta) heterodimer. This complex plays a pivotal role in the immune system by recognizing specific antigens, initiating signaling cascades that lead to B cell activation, proliferation, and differentiation. The importance of CD79B in immune responses and its implications in various clinical conditions make it a significant focus of immunological research.

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