Tumor Necrosis Factor Ligand Superfamily Member 13B / BAFF (TNFSF13B) Antibody (FITC)

Este producto es parte de TNFSF13B - TNF superfamily member 13B
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494€ (100 tests)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Tumor Necrosis Factor Ligand Superfamily Member 13B / BAFF (TNFSF13B) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx270490
tested applications
FCM

Description

Tumor Necrosis Factor Ligand Superfamily Member 13B / BAFF (TNFSF13B) Antibody (FITC) is a Rabbit Polyclonal Antibody conjugated to FITC against Tumor Necrosis Factor Ligand Superfamily Member 13B / BAFF (TNFSF13B) for use in flow cytometry.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Tumor Necrosis Factor Ligand Superfamily Member 13B / BAFF (TNFSF13B)
Host
Rabbit
Reactivity
Mouse
Recommended Dilution
FCM: 1-5 µl/106 cells. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
FITC
Isotype
IgG
Purification
Purified by antigen-specific affinity chromatography.
Size 1
100 tests
Size 2
200 tests
Size 3
500 tests
Form
Liquid
Tested Applications
FCM
Buffer
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
Availability
Please enquire.
Storage
Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q9WU72
Gene ID
24099
OMIM
603969
Alias
Tumor necrosis factor ligand superfamily member 13B,DTL,BAFF,BLYS,CD257,TALL1,THANK,ZTNF4,TALL-1,TNLG7A,TNFSF20,B lymphocyte stimulator,BLyS,Dendritic cell-derived TNF-like molecule,TNF- and APOL-related leukocyte expressed ligand 1
Background
Antibody anti-TNFSF13B
Status
RUO

Descripción

TNFSF13B, commonly known as BAFF (B-cell activating factor), is a cytokine that belongs to the tumor necrosis factor (TNF) superfamily and is critical for B cell survival, maturation, and immune function. This ligand is primarily produced by myeloid cells, such as monocytes, macrophages, and dendritic cells, but can also be secreted by activated T cells. BAFF plays a pivotal role in maintaining peripheral B cell populations, supporting antibody production, and promoting immune tolerance. It interacts with specific receptors on B cells and related immune cells, including BAFF-R, TACI (Transmembrane Activator and Calcium-Modulating Cyclophilin Ligand Interactor), and BCMA (B Cell Maturation Antigen), to initiate intracellular signaling pathways crucial for B cell homeostasis and function. Dysregulation of BAFF expression or receptor binding is associated with autoimmune diseases, such as systemic lupus erythematosus (SLE), multiple sclerosis, and rheumatoid arthritis.

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