ATP Binding Cassette Transporter A5 (ABCA5) Antibody (HRP)
169€ (20 µg)
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935106861
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name
ATP Binding Cassette Transporter A5 (ABCA5) Antibody (HRP)
category
Primary Antibodies
provider
Abbexa
reference
abx316428
tested applications
ELISA
Description
ABCA5 Antibody (HRP) is a Rabbit Polyclonal against ABCA5 conjugated to HRP.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ATP Binding Cassette Transporter A5 (ABCA5) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | HRP |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8WWZ7 |
| Gene ID | 23461 |
| NCBI Accession | NP_061142.2, NM_018672.4, NP_758424.1, NM_172232.3 |
| OMIM | 612503 |
| Alias | ABC13,HTC3 |
| Background | Antibody anti-ABCA5 |
| Status | RUO |
Descripción
ABCA5 is a member of the ATP-binding cassette (ABC) transporter family, involved in lipid transport and cellular detoxification processes. It is expressed in various tissues, including the liver, kidney, and brain, where it plays a role in maintaining lipid homeostasis and protecting cells from oxidative stress. ABCA5 utilizes ATP hydrolysis to transport lipids across membranes, contributing to processes such as cholesterol efflux and intracellular lipid trafficking. It is also associated with the regulation of lysosomal function and autophagy. Dysregulation of ABCA5 has been linked to lysosomal storage disorders and neurodegenerative diseases, highlighting its role in cellular clearance mechanisms and homeostasis.
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