ATP Binding Cassette Subfamily F Member 3 (ABCF3) Antibody
357.5€ (100 µg)
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935106861
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name
ATP Binding Cassette Subfamily F Member 3 (ABCF3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx038087
tested applications
ELISA, WB, IHC
Description
Rabbit Polyclonal against the ABCF3 protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ATP Binding Cassette Subfamily F Member 3 (ABCF3) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by Protein A/G column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | EST201864 |
| Background | Antibody anti-ABCF3 |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
ABCF3 is a member of the ABCF subfamily, characterized by its lack of transmembrane domains and its involvement in intracellular processes such as translation regulation and stress response. It is expressed in various tissues, with functions related to ribosomal activity and protein synthesis. ABCF3 is believed to play a role in modulating the translation machinery, particularly under conditions of cellular stress, enabling cells to adapt to adverse environments by selectively synthesizing stress-related proteins. Its role in maintaining protein synthesis is essential for cell survival during environmental challenges, such as oxidative stress or nutrient deprivation. Dysregulation of ABCF3 has been associated with impaired stress tolerance and altered protein homeostasis, which can contribute to pathological conditions such as neurodegenerative diseases or cancer. While its exact molecular mechanisms remain under investigation, ABCF3’s contribution to translation regulation and cellular adaptation highlights its critical role in maintaining cellular integrity and function under both normal and stress conditions.
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