ATP-Binding Cassette Subfamily B Member 9 (ABCB9) Antibody (FITC)
169€ (20 µg)
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Name
ATP-Binding Cassette Subfamily B Member 9 (ABCB9) Antibody (FITC)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx315539
Description
ABCB9 Antibody (FITC) is a Rabbit Polyclonal against ABCB9 conjugated to FITC.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: ATP-Binding Cassette Subfamily B Member 9 (ABCB9) Immunogen: Recombinant Human ATP-binding cassette sub-family B member 9 protein (630-766AA). |
| Host | Rabbit |
| Reactivity | Human |
| Detection Method | Laser Line: 488 Excitation/Emission: 499/515 |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9NP78 |
| Gene ID | 23457 |
| NCBI Accession | NP_001229942.1, NM_001243013.1, NP_001229943.1, NM_001243014.1, NP_062570.1, NM_019624.3, NP_062571.1, NM_019625.3 |
| OMIM | 605453 |
| Alias | EST122234,TAPL |
| Background | Antibody anti-ABCB9 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ABCB9, also known as TAPL (Transporter Associated with Antigen Processing-Like), is an ATP-binding cassette transporter localized to lysosomes and late endosomes. It plays a role in the transport of peptides into lysosomal compartments, contributing to processes such as antigen presentation and lysosomal proteostasis. ABCB9 contains two nucleotide-binding domains and transmembrane regions that mediate ATP-dependent peptide transport. It is expressed in various tissues, with higher levels in immune-related cells, where it supports lysosomal function and immune responses. Although its precise physiological substrates and roles remain under investigation, ABCB9’s involvement in lysosomal function underscores its importance in cellular homeostasis, immune regulation, and protein degradation pathways.
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