ATP-Binding Cassette Subfamily B Member 9 (ABCB9) Antibody

Este producto es parte de ABCB - ATP binding cassette subfamily B member
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169€ (20 µg)

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935106861
info@markelab.com
name
ATP-Binding Cassette Subfamily B Member 9 (ABCB9) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx318078
tested applications
ELISA, WB, IF/ICC

Description

ABCB9 Antibody is a Rabbit Polyclonal against ABCB9.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
ATP-Binding Cassette Subfamily B Member 9 (ABCB9)
Host
Rabbit
Reactivity
Human, Mouse
Recommended Dilution
WB: 1/500 - 1/5000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purity
> 95%
Purification
Purified by Protein G.
Size 1
20 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
1 mg
Form
Liquid
Tested Applications
ELISA, WB, IF/ICC
Buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q9NP78
Gene ID
23457
NCBI Accession
NP_001229942.1, NM_001243013.1, NP_001229943.1, NM_001243014.1, NP_062570.1, NM_019624.3, NP_062571.1, NM_019625.3
OMIM
605453
Alias
EST122234,TAPL
Background
Antibody anti-ABCB9
Status
RUO

Descripción

ABCB9, also known as TAPL (Transporter Associated with Antigen Processing-Like), is an ATP-binding cassette transporter localized to lysosomes and late endosomes. It plays a role in the transport of peptides into lysosomal compartments, contributing to processes such as antigen presentation and lysosomal proteostasis. ABCB9 contains two nucleotide-binding domains and transmembrane regions that mediate ATP-dependent peptide transport. It is expressed in various tissues, with higher levels in immune-related cells, where it supports lysosomal function and immune responses. Although its precise physiological substrates and roles remain under investigation, ABCB9’s involvement in lysosomal function underscores its importance in cellular homeostasis, immune regulation, and protein degradation pathways.

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