ATP Binding Cassette Subfamily B Member 10 (ABCB10) Antibody
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935106861
info@markelab.com
Precio
350€ (100 µg)
Antibody anti-ABCB10
proveedor
Abbexareference
abx230030Tested Applications
ELISA, WB, IPreactivity
Human, Mouse, Ratstatus
RUOclonality
PolyclonalDescripción
ABCB10 Antibody is a Rabbit Polyclonal against ABCB10.
Background
ABCB10, also known as mitochondrial ABC transporter-2, is primarily localized in the inner mitochondrial membrane and plays a critical role in mitochondrial function and heme biosynthesis. It is involved in transporting substrates required for heme production, a vital component of hemoglobin and cytochromes. ABCB10 works in coordination with other mitochondrial transporters, such as ABCB7, to ensure proper iron-sulfur cluster biogenesis and cellular redox balance. It is highly expressed in tissues with high metabolic and oxygen demands, such as the liver, heart, and erythroid cells. Dysregulation of ABCB10 has been linked to mitochondrial dysfunction and oxidative stress, contributing to conditions such as anemia and cardiovascular diseases. Its role in maintaining mitochondrial health highlights its importance in cellular energy metabolism.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human, Mouse, Rat
immunogen target
ATP Binding Cassette Subfamily B Member 10 (ABCB10)
host
Rabbit
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB, IP
purity
≥ 95% (SDS-PAGE)
purification
Purified by immunogen affinity chromatography.
buffer
PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
size 1
100 µg
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
ABCB10
dry ice
No
availability
Shipped within 5-12 working days.
alias
M-ABC2,MTABC2,EST20237
uniprot id
note
This product is for research use only.
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