ARP2 Actin Related Protein 2 Homolog (ACTR2) Antibody
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Description
Arp2 Actin-Related Protein 2 Homolog (Yeast) Antibody is a Rabbit Polyclonal antibody against Arp2 Actin-Related Protein 2 Homolog (Yeast).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ARP2 Actin Related Protein 2 Homolog (ACTR2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P61160 |
| Gene ID | 10097 |
| NCBI Accession | NP_001005386.1, NM_001005386.2, NP_005713.1, NM_005722.3 |
| OMIM | 604221 |
| Alias | ACTR2,ARP2,ARP2 |
| Background | Antibody anti-ACTR2 |
| Status | RUO |
Descripción
ACTR2 is a core component of the ARP2/3 complex, which nucleates new actin filaments in response to cellular signaling. Structurally, ACTR2, along with ACTR3, mimics the barbed end of actin filaments, initiating polymerization at branch points. It is essential for lamellipodia and filopodia formation during cell migration, phagocytosis, and endocytosis. ACTR2 is highly conserved and ubiquitously expressed. Dysregulation of ACTR2 is associated with impaired cell motility and invasion, particularly in cancer cells, where actin remodeling is critical for metastasis.
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