Actin-Related Protein 2 (ACTR2) Antibody
292.5€ (80 µl)
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935106861
info@markelab.com
name
Actin-Related Protein 2 (ACTR2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx032856
tested applications
ELISA, WB, IHC, FCM
Description
ACTR2 is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Actin-Related Protein 2 (ACTR2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, FCM |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P61160 |
| Alias | ACTR2,ARP2,ARP2 |
| Background | Antibody anti-ACTR2 |
| Status | RUO |
Descripción
ACTR2 is a core component of the ARP2/3 complex, which nucleates new actin filaments in response to cellular signaling. Structurally, ACTR2, along with ACTR3, mimics the barbed end of actin filaments, initiating polymerization at branch points. It is essential for lamellipodia and filopodia formation during cell migration, phagocytosis, and endocytosis. ACTR2 is highly conserved and ubiquitously expressed. Dysregulation of ACTR2 is associated with impaired cell motility and invasion, particularly in cancer cells, where actin remodeling is critical for metastasis.
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