ARP1 Actin Related Protein 1 Homolog A (ACTR1A) Antibody (FITC)
169€ (20 µg)
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Name
ARP1 Actin Related Protein 1 Homolog A (ACTR1A) Antibody (FITC)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx316737
Description
ACTR1A Antibody (FITC) is a Rabbit Polyclonal against ACTR1A conjugated to FITC.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: ARP1 Actin Related Protein 1 Homolog A (ACTR1A) Immunogen: Recombinant Human Alpha-centractin protein (187-376AA). |
| Host | Rabbit |
| Reactivity | Human |
| Detection Method | Laser Line: 488 Excitation/Emission: 499/515 |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P61163 |
| Gene ID | 10121 |
| OMIM | 605143 |
| Alias | ACTR1A, ARP1,CTRN1 Arp1A, centractin alpha |
| Background | Antibody anti-ACTR1A |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ACTR1A, also known as ARP1, is a key component of the dynactin complex, a regulator of dynein motor function. Structurally, ACTR1A shares homology with actin and forms a short filament within the dynactin complex. This filament acts as a scaffold for dynein-mediated retrograde transport of vesicles and organelles along microtubules. ACTR1A is highly conserved across eukaryotes, reflecting its essential role in cellular trafficking and mitotic spindle organization. Mutations or dysfunction of ACTR1A impair organelle positioning, leading to developmental and cellular abnormalities.
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