Alpha-Centractin (ACTR1A) Antibody
357.5€ (100 µg)
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Name
Alpha-Centractin (ACTR1A) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx037850
Tested Applications
ELISA, WB
Description
Rabbit Polyclonal against the ACTR1A protein.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Alpha-Centractin (ACTR1A) Immunogen: A peptide corresponding to the C-terminal region of human ACTR1A protein. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 43 kDa |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | NM_005736 |
| Alias | ACTR1A, ARP1,CTRN1 Arp1A, centractin alpha |
| Background | Antibody anti-ACTR1A |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ACTR1A, also known as ARP1, is a key component of the dynactin complex, a regulator of dynein motor function. Structurally, ACTR1A shares homology with actin and forms a short filament within the dynactin complex. This filament acts as a scaffold for dynein-mediated retrograde transport of vesicles and organelles along microtubules. ACTR1A is highly conserved across eukaryotes, reflecting its essential role in cellular trafficking and mitotic spindle organization. Mutations or dysfunction of ACTR1A impair organelle positioning, leading to developmental and cellular abnormalities.
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