Alpha-Centractin (ACTR1A) Antibody

Name: Alpha-Centractin (ACTR1A) Antibody
Brand: Abbexa
SKU: abx028607
Price: 292.5 EUR
Availability: OnlineOnly

Este producto es parte de ACTR - Actin related protein

Pida mas información

935106861

info@markelab.com

Precio

292.5€ (80 µl)

Antibody anti-ACTR1A

proveedor

Abbexa

reference

abx028607

Tested Applications

ELISA, WB

reactivity

Mouse

status

RUO

clonality

Polyclonal

Descripción

This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin.

Background

ACTR1A, also known as ARP1, is a key component of the dynactin complex, a regulator of dynein motor function. Structurally, ACTR1A shares homology with actin and forms a short filament within the dynactin complex. This filament acts as a scaffold for dynein-mediated retrograde transport of vesicles and organelles along microtubules. ACTR1A is highly conserved across eukaryotes, reflecting its essential role in cellular trafficking and mitotic spindle organization. Mutations or dysfunction of ACTR1A impair organelle positioning, leading to developmental and cellular abnormalities.

Características del producto

clonality

Polyclonal

reactivity

Mouse

immunogen target

Alpha-Centractin (ACTR1A)

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

Liquid

tested applications

ELISA, WB

purification

Purified through a protein A column, followed by peptide affinity purification.

recommended dilution

WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.

buffer

PBS containing 0.09% sodium azide.

size 1

80 µl

size 2

400 µl

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

ACTR1A

dry ice

availability

Shipped within 5-10 working days.

alias

ACTR1A, ARP1,CTRN1 Arp1A, centractin alpha

uniprot id

https://www.uniprot.org/uniprotkb/P61163

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