ArfGAP With FG Repeats 2 (AGFG2) Antibody

Este producto es parte de AGFG - Arf-GAP domain and FG repeat-containing protein
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221€ (50 µg)

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935106861
info@markelab.com
name
ArfGAP With FG Repeats 2 (AGFG2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx325607
tested applications
ELISA, WB

Description

AGFG2 Antibody is a Rabbit Polyclonal against AGFG2.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
ArfGAP With FG Repeats 2 (AGFG2)
Host
Rabbit
Reactivity
Human, Mouse
Recommended Dilution
ELISA: 1/40000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by affinity chromatography.
Size 1
50 µg
Size 2
100 µg
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
O95081
Gene ID
3268
Alias
HRBL,RABR
Background
Antibody anti-AGFG2
Status
RUO

Descripción

AGFG2 is structurally similar to AGFG1, containing both an Arf-GAP domain and FG repeats, which enable its role in vesicular trafficking and RNA transport. AGFG2 is particularly important in the context of nuclear export of RNA and is implicated in regulating the intracellular movement of proteins and nucleic acids. It is expressed across a range of tissues but is most prominent in immune cells and the nervous system, where it participates in mRNA processing and cellular signaling. Like AGFG1, AGFG2 is also exploited by certain viruses, including HIV, to facilitate the export of viral RNA, highlighting its role in host-pathogen interactions. Dysregulation of AGFG2 may contribute to defects in RNA processing and trafficking, with potential implications in immune-related diseases and viral infections. Further studies are needed to fully understand its broader physiological and pathological roles.

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