ArfGAP With FG Repeats 1 (AGFG1) Antibody

Este producto es parte de AGFG - Arf-GAP domain and FG repeat-containing protein
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637€ (100 µl)

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935106861
info@markelab.com
name
ArfGAP With FG Repeats 1 (AGFG1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx111048
tested applications
ELISA, WB, IHC

Description

Arfgap With Fg Repeats 1 Antibody is a Rabbit Polyclonal antibody against Arfgap With Fg Repeats 1.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
ArfGAP With FG Repeats 1 (AGFG1)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Antigen Affinity Chromatography.
Size 1
100 µl
Form
Liquid
Tested Applications
ELISA, WB, IHC
Buffer
PBS, pH 7.3, containing 0.02% Sodium Azide and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P52594
Gene ID
3267
NCBI Accession
NP_001128659.1, NM_001135187.1, NP_001128660.1, NM_001135188.1, NP_001128661.1, NM_001135189.1, NP_004495.2, NM_004504.4
OMIM
600862
Alias
HRB,RAB,RIP
Background
Antibody anti-AGFG1
Status
RUO

Descripción

AGFG1 is a cytoplasmic protein that plays a key role in intracellular trafficking and RNA transport. It contains an Arf-GAP domain, which facilitates the regulation of small GTPases involved in vesicle formation, and FG repeats, which mediate interactions with nuclear pore complexes and RNA-binding proteins. AGFG1 is highly expressed in tissues such as the brain, immune cells, and reproductive tissues, where it participates in mRNA transport and localization. It is also involved in the HIV life cycle, specifically in the nuclear export of viral RNA, making it a potential therapeutic target for antiviral strategies. Dysregulation of AGFG1 has been associated with disruptions in intracellular transport and immune signaling, with emerging evidence suggesting its involvement in diseases such as viral infections and possibly cancer.

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