Arf-GAP With Coiled-Coil, ANK Repeat And PH Domain Containing Protein 2 (ACAP2) Antibody
351€ (100 µg)
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935106861
info@markelab.com
name
Arf-GAP With Coiled-Coil, ANK Repeat And PH Domain Containing Protein 2 (ACAP2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx375503
tested applications
ELISA, WB
Description
Arf-GAP With Coiled-Coil, ANK Repeat And PH Domain Containing Protein 2 (ACAP2) Antibody is a Rabbit Polyclonal antibody against Arf-GAP With Coiled-Coil, ANK Repeat And PH Domain Containing Protein 2 (ACAP2).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Arf-GAP With Coiled-Coil, ANK Repeat And PH Domain Containing Protein 2 (ACAP2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q15057 |
| Gene ID | 23527 |
| Alias | CENTB2,CNT-B2,Centaurin beta 2 |
| Background | Antibody anti-ACAP2 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
ACAP2, a GTPase-activating protein for Arf proteins, regulates vesicular trafficking and membrane remodeling. Its PH domain, ankyrin repeats, and coiled-coil motifs facilitate interactions with phospholipids and proteins. ACAP2 is involved in endocytic recycling, actin cytoskeleton dynamics, and signaling pathways, particularly in neurons where it supports synaptic plasticity and neurotransmission by trafficking vesicles and receptors. It also regulates cell migration and polarity, aiding tissue development and repair. Dysregulation of ACAP2 has been associated with neurodegenerative diseases and cancer metastasis, reflecting its essential role in maintaining cellular trafficking and structural integrity.
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