Arf-GAP With Coiled-Coil, ANK Repeat And PH Domain Containing Protein 2 (ACAP2) Antibody
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935106861
info@markelab.com
Precio
195€ (20 µl)
Antibody anti-ACAP2
proveedor
Abbexareference
abx125484Tested Applications
ELISA, WB, IF/ICCreactivity
Human, Mousestatus
RUOclonality
PolyclonalDescripción
ACAP2 Antibody is a Rabbit Polyclonal against ACAP2.
Background
ACAP2, a GTPase-activating protein for Arf proteins, regulates vesicular trafficking and membrane remodeling. Its PH domain, ankyrin repeats, and coiled-coil motifs facilitate interactions with phospholipids and proteins. ACAP2 is involved in endocytic recycling, actin cytoskeleton dynamics, and signaling pathways, particularly in neurons where it supports synaptic plasticity and neurotransmission by trafficking vesicles and receptors. It also regulates cell migration and polarity, aiding tissue development and repair. Dysregulation of ACAP2 has been associated with neurodegenerative diseases and cancer metastasis, reflecting its essential role in maintaining cellular trafficking and structural integrity.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human, Mouse
immunogen target
Arf-GAP With Coiled-Coil, ANK Repeat And PH Domain Containing Protein 2 (ACAP2)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB, IF/ICC
purification
Purified by affinity chromatography.
recommended dilution
ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
size 1
20 µl
size 2
100 µl
size 3
2 × 100 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
ACAP2
dry ice
No
availability
Shipped within 5-10 working days.
alias
CENTB2,CNT-B2,Centaurin beta 2
uniprot id
NCBI accession
NP_036419.3
note
Concentration: > 0.2 mg/ml -
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