Arf-GAP With Coiled-Coil, ANK Repeat And PH Domain Containing Protein 2 (ACAP2) Antibody

Este producto es parte de ACAP - Arf-GAP With Coiled-Coil, ANK Repeat And PH Domain Containing Protein
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195€ (20 µl)

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935106861
info@markelab.com
name
Arf-GAP With Coiled-Coil, ANK Repeat And PH Domain Containing Protein 2 (ACAP2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx125484
tested applications
ELISA, WB, IF/ICC

Description

ACAP2 Antibody is a Rabbit Polyclonal against ACAP2.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Arf-GAP With Coiled-Coil, ANK Repeat And PH Domain Containing Protein 2 (ACAP2)
Host
Rabbit
Reactivity
Human, Mouse
Recommended Dilution
ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by affinity chromatography.
Size 1
20 µl
Size 2
100 µl
Size 3
2 × 100 µl
Form
Liquid
Tested Applications
ELISA, WB, IF/ICC
Buffer
PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q15057
Gene ID
23527
NCBI Accession
NP_036419.3
Alias
CENTB2,CNT-B2,Centaurin beta 2
Background
Antibody anti-ACAP2
Status
RUO
Note
Concentration: > 0.2 mg/ml - 

Descripción

ACAP2, a GTPase-activating protein for Arf proteins, regulates vesicular trafficking and membrane remodeling. Its PH domain, ankyrin repeats, and coiled-coil motifs facilitate interactions with phospholipids and proteins. ACAP2 is involved in endocytic recycling, actin cytoskeleton dynamics, and signaling pathways, particularly in neurons where it supports synaptic plasticity and neurotransmission by trafficking vesicles and receptors. It also regulates cell migration and polarity, aiding tissue development and repair. Dysregulation of ACAP2 has been associated with neurodegenerative diseases and cancer metastasis, reflecting its essential role in maintaining cellular trafficking and structural integrity.

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