Archaemetzincin-2 (AMZ2) Antibody
260€ (50 µl)
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935106861
info@markelab.com
name
Archaemetzincin-2 (AMZ2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx339814
tested applications
ELISA, IHC
Description
AMZ2 Antibody is a Rabbit Polyclonal against AMZ2.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Archaemetzincin-2 (AMZ2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/1000 - 1/5000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q86W34 |
| Gene ID | 51321 |
| Alias | AMZ2 |
| Background | Antibody anti-AMZ2 |
| Status | RUO |
Descripción
AMZ2, like AMZ1, is a zinc-dependent metallopeptidase that functions in the regulation of protein degradation and extracellular matrix remodeling. AMZ2 is widely expressed in tissues, including those involved in immune responses and connective tissue maintenance. AMZ2 has been shown to play a role in proteolytic processes that modulate cellular signaling pathways, tissue repair, and organ development. Its enzymatic activity depends on zinc ions, which are essential for stabilizing the active site and facilitating substrate cleavage. AMZ2 is involved in regulating inflammatory processes by processing bioactive peptides and matrix proteins, contributing to tissue remodeling during immune responses and injury repair. Dysregulation of AMZ2 has been associated with chronic inflammation, cancer progression, and neurodegenerative diseases, where altered proteolytic activity can disrupt tissue integrity and cellular signaling. AMZ2 is emerging as a potential target for therapeutic interventions aimed at modulating protease activity in pathological conditions.
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