AP-4 Complex Subunit Mu-1 (AP4M1) Antibody
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Description
Rabbit Polyclonal against the AP4M1 protein.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | AP-4 Complex Subunit Mu-1 (AP4M1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | AP4M1,MUARP2 |
| Background | Antibody anti-AP4M1 |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
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Component of the AP-4 complex, a novel type of clathrin-or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network(TGN) to the endosomal-lysosomal system. Plays a role in the intracellular trafficking of APP from the trans-Golgi network(TGN) to endosomes, and thereby inhibits amyloidogenic processing of APP.
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AP-4 Complex Subunit Mu-1 (AP4M1) Antibody
This gene encodes a subunit of the heterotetrameric AP-4 complex. The encoded protein belongs to the adaptor complexes medium subunits family. This AP-4 complex is involved in the recognition and sorting of cargo proteins with tyrosine-based motifs from the trans-golgi network to the endosomal-lysosomal system.
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