AP4M1 antibody
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Description
Component of the AP-4 complex, a novel type of clathrin-or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network(TGN) to the endosomal-lysosomal system. Plays a role in the intracellular trafficking of APP from the trans-Golgi network(TGN) to endosomes, and thereby inhibits amyloidogenic processing of APP.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | adaptor-related protein complex 4, mu 1 subunit (AP4M1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 50-55 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | O00189 |
| Gene ID | 9179 |
| Alias | AP-4 complex subunit mu-1,AP-4 adaptor complex mu subunit,Adaptor-related protein complex 4 subunit mu-1,Mu subunit of AP-4,Mu-adaptin-related protein 2 (mu-ARP2),Mu4-adaptin (mu4),AP4M1,MUARP2 |
| Background | Antibody anti-AP4M1 |
| Status | RUO |
| Note | Mol. Weight 50-55 kDa |
Descripción
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AP4M1 antibody
Component of the AP-4 complex, a novel type of clathrin-or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network(TGN) to the endosomal-lysosomal system. Plays a role in the intracellular trafficking of APP from the trans-Golgi network(TGN) to endosomes, and thereby inhibits amyloidogenic processing of APP.
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AP-4 Complex Subunit Mu-1 (AP4M1) Antibody
This gene encodes a subunit of the heterotetrameric AP-4 complex. The encoded protein belongs to the adaptor complexes medium subunits family. This AP-4 complex is involved in the recognition and sorting of cargo proteins with tyrosine-based motifs from the trans-golgi network to the endosomal-lysosomal system.
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