anti- YWHAB antibody

Descripción

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form(by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2. Negative regulator of signaling cascades that mediate activatation of MAP kinases via AKAP13.

Características del producto

clonality

polyclonal

reactivity

human,mouse,rat

immunogen target

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

liquid

tested applications

ELISA, IHC

observerd MW

28 kDa

purity

≥95% as determined by SDS-PAGE

purification

Immunogen affinity purified

recommended dilution

IHC: 1:20-1:200

size 1

100µg

storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

or code

YWHAB

alias

YWHAB, GW128, HEL-S-1, HS1, KCIP-1, YWHAA, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta,14-3-3 alpha,14-3-3 beta

uniprot id

https://www.uniprot.org/uniprotkb/P31946

gene id

https://www.ncbi.nlm.nih.gov/gene/7529

note

This product is for research use only.

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Human YWHAB(14-3-3 protein Beta/Alpha) ELISA Kit

proveedor

FineTest

reference

EH4008

reactivity

human

status

RUO

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