XRN1 antibody
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935106861
info@markelab.com
name
XRN1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab09556
tested applications
ELISA, WB, IHC, IF
Description
Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA(By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma(OGS).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | 5'-3' exoribonuclease 1 (XRN1) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 192 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q8IZH2 |
| Gene ID | 54464 |
| Alias | 5'-3' exoribonuclease 1,Strand-exchange protein 1 homolog,XRN1,45536 |
| Background | Antibody anti-XRN1 |
| Status | RUO |
| Note | Mol. Weight 192 kDa |
Descripción
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