5'-3'Exoribonuclease 1 (XRN1) Antibody

Name: 5'-3'Exoribonuclease 1 (XRN1) Antibody
Brand: Abbexa
SKU: abx131575
Price: 286 EUR
Availability: OnlineOnly

286€ (100 µl)

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5'-3'Exoribonuclease 1 (XRN1) Antibody

Description

5'-3'Exoribonuclease 1 Antibody is a Rabbit Polyclonal against 5'-3'Exoribonuclease 1.

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Product specifications

Category	Primary Antibodies
Immunogen Target	Target: 5'-3'Exoribonuclease 1 (XRN1) Immunogen: XRN1 (Tyr1394-Glu1706)
Host	Rabbit
Reactivity	Human
Assay Type	Concentration: 0.62 mg/ml
Recommended Dilution	WB (Predicted): 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC (Predicted): 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
Clonality	Polyclonal
Conjugation	Unconjugated
Purification	Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography.
Size 1	100 µl
Size 2	200 µl
Size 3	1 ml
Form	Liquid
Tested Applications	IHC
Buffer	0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
Availability	Shipped within 5-7 working days.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice	No
UniProt ID	Q8IZH2
Background	Antibody anti-XRN1
Status	RUO
Note	THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Descripción

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XRN1 antibody

Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA(By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma(OGS).

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