5'-3'Exoribonuclease 1 (XRN1) Antibody

286€ (100 µl)
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935106861
info@markelab.com
name
5'-3'Exoribonuclease 1 (XRN1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx131575
tested applications
WB, IHC, IF/ICC
Description
5'-3'Exoribonuclease 1 Antibody is a Rabbit Polyclonal against 5'-3'Exoribonuclease 1.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | 5'-3'Exoribonuclease 1 (XRN1) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
Size 1 | 100 µl |
Size 2 | 200 µl |
Size 3 | 1 ml |
Form | Liquid |
Tested Applications | WB, IHC, IF/ICC |
Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
Availability | Shipped within 5-7 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
Background | Antibody anti-XRN1 |
Status | RUO |
Note | Concentration: 0.62 mg/ml - |
Descripción
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Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA(By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma(OGS).
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