USP37 antibody
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935106861
info@markelab.com
name
USP37 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab09330
tested applications
ELISA, WB
Description
Deubiquitinase that antagonizes the anaphase-promoting complex(APC/C) during G1/S transition by mediating deubiquitination of cyclin-A(CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of 'Lys-11'-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A(CCNA1 and CCNA2).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ubiquitin specific peptidase 37 (USP37) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:5000; IP: 1:200-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 110 kDa,70 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q86T82 |
| Gene ID | 57695 |
| Alias | Ubiquitin carboxyl-terminal hydrolase 37,Deubiquitinating enzyme 37,Ubiquitin thioesterase 37,Ubiquitin-specific-processing protease 37,USP37,KIAA1594 |
| Background | Antibody anti-USP37 |
| Status | RUO |
| Note | Mol. Weight 110 kDa, 70 kDa |
Descripción
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