UNC5C, also named as UNC5H3, belongs to the unc-5 family. It is a receptor for netrin required for axon guidance. It mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also involved in corticospinal tract axon guidances independently of DCC. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. The antibody is specific to UNC5C.
Primary Antibodies
polyclonal
human,mouse,rat
unc-5 homolog C(C. elegans)
Rabbit
IgG
Unconjugated
liquid
ELISA, WB
103 kDa
≥95% as determined by SDS-PAGE
Immunogen affinity purified
WB: 1:500-1:5000
100µg
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UNC5C
UNC5H3,Protein unc-5 homolog 3,Protein unc-5 homolog C,Netrin receptor UNC5C
This product is for research use only.
Precio a consultar
Ver másUNC5C, also named as UNC5H3, belongs to the unc-5 family. It is a receptor for netrin required for axon guidance. It med...
Precio a consultar
Ver másReceptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervo...
281.25€ (80 µl)
Ver más