UBR2 antibody
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
UBR2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab09209
tested applications
ELISA, WB, IF, IHC
Description
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Plays a critical role in chromatin inactivation and chromosome-wide transcriptional silencing during meiosis via ubiquitination of histone H2A. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ubiquitin protein ligase E3 component n-recognin 2 (UBR2) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:200-1:2000; IF:1:10-1:100; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 66 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q8IWV8 |
| Gene ID | 23304 |
| Alias | E3 ubiquitin-protein ligase UBR2,N-recognin-2,RING-type E3 ubiquitin transferase UBR2,Ubiquitin-protein ligase E3-alpha-2,Ubiquitin-protein ligase E3-alpha-II,UBR2,C6orf133,KIAA0349 |
| Background | Antibody anti-UBR2 |
| Status | RUO |
| Note | Mol. Weight 66 kDa |
Descripción
Related Products
UBR2 antibody
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Plays a critical role in chromatin inactivation and chromosome-wide transcriptional silencing during meiosis via ubiquitination of histone H2A. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth.
Ver Producto
E3 Ubiquitin-Protein Ligase UBR2 (UBR2) Antibody
UBR2 Antibody is a Rabbit Polyclonal antibody against UBR2.
Ver Producto
E3 Ubiquitin-Protein Ligase UBR2 (UBR2) Antibody
UBR2 Antibody is a Rabbit Polyclonal against UBR2.
Ver Producto