BAG4 antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | BCL2-associated athanogene 4 (BAG4) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 60 kDa, 66-70 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | O95429 |
| Alias | BAG-4,SODD,Bcl-2-associated athanogene 4,Silencer of death domains,BAG family molecular chaperone regulator 4 |
| Background | Antibody anti-BAG4 |
| Status | RUO |
| Note | Mol. Weight 60 kDa, 66-70 kDa |
Related Products
BAG4 antibody
Ver Producto
BAG Family Molecular Chaperone Regulator 4 (BAG4) Antibody
Rabbit polyclonal antibody against BAG4 protein. Immunogen region is C-terminal.
Ver Producto
BAG Family Molecular Chaperone Regulator 4 (BAG4) Antibody
BAG4 is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost.
Ver Producto