anti- RXRG antibody

Este producto es parte de RXR - retinoid X receptor
anti- RXRG antibody

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935106861

info@markelab.com

Precio

Precio a consultar

Antibody anti-RXRG

proveedor

FineTest

reference

FNab07545

Tested Applications

ELISA, WB

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

Descripción

Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements(RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid(By similarity).


Background

Retinoid X receptor gamma (RXRG) is another retinoid X receptor involved in regulating gene expression and cellular processes in response to retinoids RXRG shares many of the functions of RXRA and RXRB but is particularly involved in regulating genes related to energy metabolism, cell differentiation, and inflammation RXRG plays a key role in the regulation of lipid metabolism, glucose homeostasis, and the response to oxidative stress It is expressed in tissues such as adipose tissue, skeletal muscle, and the liver, where it helps control the transcription of genes involved in fat storage and energy utilization RXRG is also involved in regulating immune function and inflammation, particularly in the context of autoimmune diseases and inflammatory disorders Dysregulation of RXRG is associated with metabolic diseases like obesity, diabetes, and fatty liver disease, as well as certain cancers Its involvement in immune regulation and metabolic pathways makes RXRG a critical factor in maintaining overall homeostasis RXRG represents a potential therapeutic target for treating metabolic and inflammatory diseases, as well as cancers, by modulating its role in lipid metabolism, inflammation, and cell differentiation

Características del producto

category

Primary Antibodies


clonality

polyclonal


reactivity

human,mouse,rat


immunogen target

retinoid X receptor, gamma


host

Rabbit


isotype

IgG


conjugation

Unconjugated


form

liquid


tested applications

ELISA, WB


observerd MW

51-55 kDa


purity

≥95% as determined by SDS-PAGE


purification

Immunogen affinity purified


recommended dilution

WB: 1:500-1:2000


size 1

100µg


storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)


or code

RXRG


alias

RXRC,NR2B3,RXRgamma,RXR-gamma,Retinoic acid receptor RXR-gamma,Retinoid X receptor gamma,Nuclear receptor subfamily 2 group B member 3


note

This product is for research use only.


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