anti- RXRG antibody
Pida mas información
935106861
info@markelab.com
Precio
Precio a consultar
Antibody anti-RXRG
proveedor
FineTestreference
FNab07545Tested Applications
ELISA, WBreactivity
human,mouse,ratstatus
RUOclonality
polyclonalDescripción
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements(RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid(By similarity).
Background
Retinoid X receptor gamma (RXRG) is another retinoid X receptor involved in regulating gene expression and cellular processes in response to retinoids RXRG shares many of the functions of RXRA and RXRB but is particularly involved in regulating genes related to energy metabolism, cell differentiation, and inflammation RXRG plays a key role in the regulation of lipid metabolism, glucose homeostasis, and the response to oxidative stress It is expressed in tissues such as adipose tissue, skeletal muscle, and the liver, where it helps control the transcription of genes involved in fat storage and energy utilization RXRG is also involved in regulating immune function and inflammation, particularly in the context of autoimmune diseases and inflammatory disorders Dysregulation of RXRG is associated with metabolic diseases like obesity, diabetes, and fatty liver disease, as well as certain cancers Its involvement in immune regulation and metabolic pathways makes RXRG a critical factor in maintaining overall homeostasis RXRG represents a potential therapeutic target for treating metabolic and inflammatory diseases, as well as cancers, by modulating its role in lipid metabolism, inflammation, and cell differentiation
Características del producto
category
Primary Antibodies
clonality
polyclonal
reactivity
human,mouse,rat
immunogen target
retinoid X receptor, gamma
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
liquid
tested applications
ELISA, WB
observerd MW
51-55 kDa
purity
≥95% as determined by SDS-PAGE
purification
Immunogen affinity purified
recommended dilution
WB: 1:500-1:2000
size 1
100µg
storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
or code
RXRG
alias
RXRC,NR2B3,RXRgamma,RXR-gamma,Retinoic acid receptor RXR-gamma,Retinoid X receptor gamma,Nuclear receptor subfamily 2 group B member 3
uniprot id
note
This product is for research use only.
Quizá le pueda interesar
Mouse Rxrg(Retinoic acid receptor RXR-gamma) ELISA Kit
proveedor
FineTestreference
EM0589reactivity
mousestatus
RUOPrecio a consultar
Ver másanti- RXRG antibody
proveedor
FineTestreference
FNab07545Tested Applications
ELISA, WBreactivity
human,mouse,ratstatus
RUOclonality
polyclonalReceptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response t...
Precio a consultar
Ver másRetinoid X Receptor Gamma (RXRG) Antibody
proveedor
Abbexareference
abx013188Tested Applications
WB, IHC, IF/ICCreactivity
Human, Mousestatus
RUOclonality
PolyclonalRabbit polyclonal antibody against Retinoid X Receptor gamma protein. Immunogen region is Internal.
43.75€ (10 µg)
Ver más