anti- RAB4A antibody

Este producto es parte de RAB - member RAS oncogene family
anti- RAB4A antibody

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935106861

info@markelab.com

Precio

Precio a consultar

Antibody anti-RAB4A

proveedor

FineTest

reference

FNab07037

Tested Applications

ELISA, WB,IHC,IF

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

Descripción

The human RAB genes share structural and biochemical properties with the Ras gene superfamily, and RAB4(synonym: RAB4A) is a small GTPase belonging to this Ras superfamily. Accumulating data suggests an important role for RAB proteins either in endocytosis or in biosynthetic protein transport. The transport of newly synthesized proteins from endoplasmic reticulum to the Golgi complex and to secretory vesicles involves the movement of carrier vesicles, a process that appears to involve RAB protein function. RAB4 may also function as regulator along the receptor recycling pathway.


Background

RAB4A, member RAS oncogene family (RAB4A) is a small GTPase that is part of the RAS superfamily, which plays a critical role in regulating intracellular vesicular trafficking and membrane dynamics RAB4A is particularly involved in early endosomal trafficking and recycling, contributing to the movement of endosomes between cellular compartments and facilitating the recycling of receptors and other proteins back to the plasma membrane It plays a role in the regulation of cell surface receptor availability and function, affecting processes like endocytosis, cell signaling, and vesicle trafficking Dysregulation of RAB4A has been associated with various diseases, including cancer, where altered vesicular trafficking can lead to changes in cell growth, adhesion, and migration Furthermore, RAB4A is also implicated in processes such as the immune response and neuronal signaling, making it an important protein for both immune function and cellular communication

Características del producto

category

Primary Antibodies


clonality

polyclonal


reactivity

human,mouse,rat


immunogen target

RAB4A, member RAS oncogene family


host

Rabbit


isotype

IgG


conjugation

Unconjugated


form

liquid


tested applications

ELISA, WB,IHC,IF


observerd MW

26 kDa


purity

≥95% as determined by SDS-PAGE


purification

Immunogen affinity purified


recommended dilution

WB: 1:200-1:1000; IHC: 1:50-1:500; IF: 1:20-1:200


size 1

100µg


storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)


or code

RAB4A


alias

RAB4,HRES1,HRES-1,HRES-1/RAB4,Ras-related protein Rab-4A


note

This product is for research use only.


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