Negatively regulates TCR(T-cell antigen receptor)-mediated signaling in T-cells and FCER1(high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling.
Primary Antibodies
polyclonal
human,mouse
phosphoprotein associated with glycosphingolipid microdomains 1
Rabbit
IgG
Unconjugated
liquid
ELISA, WB
50-60 kDa
≥95% as determined by SDS-PAGE
Immunogen affinity purified
WB: 1:500-1:2000
100µg
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
PAG1
PAG1, CBP, PAG, phosphoprotein membrane anchor with glycosphingolipid microdomains 1
This product is for research use only.
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Ver másNegatively regulates TCR(T-cell antigen receptor)-mediated signaling in T-cells and FCER1(high affinity immunoglobulin e...
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Ver másPhosphoprotein Associated With Glycosphingolipid Microdomains 1 Antibody is a Rabbit Polyclonal against Phosphoprotein A...
275€ (100 µl)
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