anti- NUP85 antibody

Descripción

Essential component of the nuclear pore complex(NPC) that seems to be required for NPC assembly and maintenance. As part of the NPC Nup107-160 subcomplex plays a role in RNA export and in tethering NUP98/Nup98 and NUP153 to the nucleus. The Nup107-160 complex seems to be required for spindle assembly during mitosis. NUP85 is required for membrane clustering of CCL2-activated CCR2. Seems to be involved in CCR2-mediated chemotaxis of monocytes and may link activated CCR2 to the phosphatidyl-inositol 3-kinase-Rac-lammellipodium protrusion cascade.

Características del producto

clonality

polyclonal

reactivity

human,mouse

immunogen target

nucleoporin 85kDa

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

liquid

tested applications

ELISA, WB, IHC, IF

observerd MW

70-75kd

purity

≥95% as determined by SDS-PAGE

purification

Immunogen affinity purified

recommended dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

size 1

100µg

storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

or code

NUP85

alias

Nup75,FROUNT,NPHS17,nucleoporin 85kDa,Nuclear pore complex protein Nup85,Nucleoporin Nup75,Nucleoporin Nup85,Pericentrin-1

uniprot id

https://www.uniprot.org/uniprotkb/Q9BW27

gene id

https://www.ncbi.nlm.nih.gov/gene/79902

note

This product is for research use only.

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