NUP62CL antibody

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935106861
info@markelab.com
name
NUP62CL antibody
category
Primary Antibodies
provider
FineTest
reference
FNab05928
tested applications
ELISA, WB
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | nucleoporin 62kDa C-terminal like (NUP62CL) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | WB: 1:500-1:2000 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 30 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | Q9H1M0 |
Gene ID | 54830 |
Alias | NUP62L,nucleoporin 62kDa C-terminal like |
Background | Antibody anti-NUP62CL |
Status | RUO |
Note | Mol. Weight 30 kDa |
Nucleoporin 62 C-Terminal Like (NUP62CL) is a protein homologous to the C-terminal domain of NUP62, a key component of the nuclear pore complex (NPC). The NPC is crucial for nucleocytoplasmic transport, facilitating the selective exchange of macromolecules such as RNA and proteins between the nucleus and cytoplasm. While the specific role of NUP62CL is less defined, it is thought to contribute to NPC-associated processes, potentially influencing transport dynamics or structural integrity of the pore complex. Emerging evidence suggests that NUP62CL may have tissue-specific or context-dependent functions, possibly in specialized forms of transport regulation or in the assembly of nuclear pores under specific conditions. Dysregulation of nucleoporins, including NUP62CL, has been implicated in diseases such as cancer and neurodegenerative disorders, highlighting the importance of NPC components in maintaining cellular homeostasis. Further research is needed to uncover the precise biological and pathological roles of NUP62CL.
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