NUP62CL antibody

Este producto es parte de NUP - nucleoporin
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935106861
info@markelab.com
name
NUP62CL antibody
category
Primary Antibodies
provider
FineTest
reference
FNab05928
tested applications
ELISA, WB

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
nucleoporin 62kDa C-terminal like (NUP62CL)
Host
Rabbit
Reactivity
Human
Recommended Dilution
WB: 1:500-1:2000
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
30 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q9H1M0
Gene ID
54830
Alias
NUP62L,nucleoporin 62kDa C-terminal like
Background
Antibody anti-NUP62CL
Status
RUO
Note
Mol. Weight 30 kDa

Nucleoporin 62 C-Terminal Like (NUP62CL) is a protein homologous to the C-terminal domain of NUP62, a key component of the nuclear pore complex (NPC). The NPC is crucial for nucleocytoplasmic transport, facilitating the selective exchange of macromolecules such as RNA and proteins between the nucleus and cytoplasm. While the specific role of NUP62CL is less defined, it is thought to contribute to NPC-associated processes, potentially influencing transport dynamics or structural integrity of the pore complex. Emerging evidence suggests that NUP62CL may have tissue-specific or context-dependent functions, possibly in specialized forms of transport regulation or in the assembly of nuclear pores under specific conditions. Dysregulation of nucleoporins, including NUP62CL, has been implicated in diseases such as cancer and neurodegenerative disorders, highlighting the importance of NPC components in maintaining cellular homeostasis. Further research is needed to uncover the precise biological and pathological roles of NUP62CL.

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