MAG antibody

Este producto es parte de MAG - myelin associated glycoprotein
MAG antibody
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Name
MAG antibody
Category
Primary Antibodies
Provider
FineTest
Reference
FNab04932
Tested Applications
ELISA, WB

Description

Adhesion molecule in postnatal neural development that mediates sialic-acid dependent cell-cell interactions between neuronal and myelinating cells. Preferentially binds to alpha-2,3-linked sialic acid(By similarity).

Documentos del producto

Instrucciones
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Data sheet
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Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
myelin associated glycoprotein (MAG)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500-1:2000
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
100 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
P20916
Gene ID
4099
Alias
GMA,S-MAG,SPG75,SIGLEC4,SIGLEC4A,SIGLEC-4A
Background
Antibody anti-MAG
Status
RUO
Note
Mol. Weight 100 kDa

Background

Myelin Associated Glycoprotein (MAG) is a type I transmembrane glycoprotein that plays a crucial role in the nervous system. It is predominantly found in the myelin sheath, a protective covering that surrounds nerve fibers (axons) in both the central nervous system (CNS) and the peripheral nervous system (PNS). MAG is essential for the maintenance of myelin integrity, axon-myelin interactions, and the regulation of axonal growth and regeneration. It belongs to the immunoglobulin superfamily, which is characterized by the presence of immunoglobulin-like domains. MAG's functions are vital for proper neuronal signaling and overall nervous system health.

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