MAG antibody
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935106861
info@markelab.com
name
MAG antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04932
tested applications
ELISA, WB
Description
Adhesion molecule in postnatal neural development that mediates sialic-acid dependent cell-cell interactions between neuronal and myelinating cells. Preferentially binds to alpha-2,3-linked sialic acid(By similarity).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | myelin associated glycoprotein (MAG) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 100 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P20916 |
| Gene ID | 4099 |
| Alias | GMA,S-MAG,SPG75,SIGLEC4,SIGLEC4A,SIGLEC-4A |
| Background | Antibody anti-MAG |
| Status | RUO |
| Note | Mol. Weight 100 kDa |
Descripción
Myelin Associated Glycoprotein (MAG) is a type I transmembrane glycoprotein that plays a crucial role in the nervous system. It is predominantly found in the myelin sheath, a protective covering that surrounds nerve fibers (axons) in both the central nervous system (CNS) and the peripheral nervous system (PNS). MAG is essential for the maintenance of myelin integrity, axon-myelin interactions, and the regulation of axonal growth and regeneration. It belongs to the immunoglobulin superfamily, which is characterized by the presence of immunoglobulin-like domains. MAG's functions are vital for proper neuronal signaling and overall nervous system health.
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MAG antibody
Adhesion molecule in postnatal neural development that mediates sialic-acid dependent cell-cell interactions between neuronal and myelinating cells. Preferentially binds to alpha-2,3-linked sialic acid(By similarity).
Ver Producto