anti- LRRC52 antibody
Contáctenos para saber el precio
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
anti- LRRC52 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04860
tested applications
ELISA, WB
Descripción del producto
Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel(BK alpha). Modulates gating properties by producing a marked shift in the BK channel's voltage dependence of activation in the hyperpolarizing direction, and in the absence of calcium. KCNU1 channel auxiliary protein. May modulate KCNU1 gating properties.
Documents del producto
Instrucciones
Data sheet
Especificaciones del producto
| Alias | BK channel auxiliary gamma subunit LRRC52 |
| Background | Antibody anti-LRRC52 |
| Category | Primary Antibodies |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Form | liquid |
| Gene ID | 440699 |
| Host | Rabbit |
| Immunogen Target | leucine rich repeat containing 52 |
| Isotype | IgG |
| Name | anti- LRRC52 antibody |
| Note | This product is for research use only. |
| Observed MW | 45 kDa |
| Provider | FineTest |
| Purification | Immunogen affinity purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Reactivity | human,mouse |
| Recommended Dilution | WB: 1:500-1:2000 |
| Reference | FNab04860 |
| Size 1 | 100µg |
| Status | RUO |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Tested Applications | ELISA, WB |
| UniProt ID | Q8N7C0 |
Descripcion del producto en español
Background en español
LRRC52 is an auxiliary subunit of large-conductance calcium-activated potassium (BK) channels predominantly expressed in smooth muscle tissues and neurons it modulates the gating properties of BK channels influencing their sensitivity to voltage and calcium signaling this regulation is critical for cellular excitability and processes such as smooth muscle contraction and neurotransmitter release LRRC52 has been implicated in the control of vascular tone and neuronal signaling playing a role in conditions such as hypertension and neurological disorders studies suggest its expression is essential for proper reproductive function as it regulates ion channel activity in sperm further research is exploring its role in diseases such as epilepsy and hypertension where BK channel dysfunction contributes to pathophysiology LRRC52's interactions with other channel subunits and its regulatory mechanisms are key areas of ongoing investigation aimed at identifying novel therapeutic strategies targeting ion channel dysregulation
Related Products
anti- LRRC52 antibody
Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel(BK alpha). Modulates gating properties by producing a marked shift in the BK channel's voltage dependence of activation in the hyperpolarizing direction, and in the absence of calcium. KCNU1 channel auxiliary protein. May modulate KCNU1 gating properties.
Ver Producto
Leucine Rich Repeat Containing 52 (LRRC52) Antibody
LRRC52 Antibody is a Rabbit Polyclonal antibody against LRRC52.
Ver Producto
Leucine Rich Repeat Containing 52 (LRRC52) Antibody
LRRC52 Antibody is a Rabbit Polyclonal against LRRC52.
Ver Producto