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The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.
Primary Antibodies
polyclonal
human,mouse,rat
karyopherin alpha 4 (importin alpha 3)
Rabbit
IgG
Unconjugated
liquid
ELISA, WB, IHC, IF
59 kDa
≥95% as determined by SDS-PAGE
Immunogen affinity purified
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
100µg
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
KPNA4
KPNA4,IPOA3, QIP1, SRP3, Importin subunit alpha-3
This product is for research use only.
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