anti- IL2 antibody
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Precio
Precio a consultar
Antibody anti-IL2
proveedor
FineTestreference
FNab09820Tested Applications
ELISA, WB, IHCreactivity
humanstatus
RUOclonality
polyclonalDescripción
The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.
Background
Interleukin-2 (IL2) is a key cytokine that plays a crucial role in the immune system, particularly in the activation and regulation of immune responses. First discovered in 1976, IL-2 was initially referred to as "T-cell growth factor" due to its role in the proliferation of T cells, a vital component of the immune system. IL-2 has since become recognized as one of the most important cytokines for maintaining immune homeostasis and enhancing the activity of immune cells, including natural killer (NK) cells, B cells, and T cells. Its role in immune modulation has significant implications in both health and disease, including cancer, autoimmune diseases, and infections.
Características del producto
category
Primary Antibodies
clonality
polyclonal
reactivity
human
immunogen target
interleukin 2
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
liquid
tested applications
ELISA, WB, IHC
observerd MW
22 kDa
purity
≥95% as determined by SDS-PAGE
purification
Immunogen affinity purified
recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
size 1
100µg
storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
or code
IL2
alias
IL-2,TCGF,lymphokine,T-cell growth factor
uniprot id
note
This product is for research use only.
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