IL2 antibody

Este producto es parte de IL2 - interleukin 2
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935106861
info@markelab.com
name
IL2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab09820
tested applications
ELISA, WB, IHC

Description

The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
interleukin 2 (IL2)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
22 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
UniProt ID
P60568
Gene ID
3558
Alias
IL-2,TCGF,lymphokine,T-cell growth factor
Background
Antibody anti-IL2
Status
RUO
Note
Mol. Weight 22 kDa

Descripción

Interleukin-2 (IL2) is a key cytokine that plays a crucial role in the immune system, particularly in the activation and regulation of immune responses. First discovered in 1976, IL-2 was initially referred to as "T-cell growth factor" due to its role in the proliferation of T cells, a vital component of the immune system. IL-2 has since become recognized as one of the most important cytokines for maintaining immune homeostasis and enhancing the activity of immune cells, including natural killer (NK) cells, B cells, and T cells. Its role in immune modulation has significant implications in both health and disease, including cancer, autoimmune diseases, and infections.

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