anti- IL2 antibody

Este producto es parte de IL2 - interleukin 2
anti- IL2 antibody

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935106861

info@markelab.com

Precio

Precio a consultar

Antibody anti-IL2

proveedor

FineTest

reference

FNab09820

Tested Applications

ELISA, WB, IHC

reactivity

human

status

RUO

clonality

polyclonal

Descripción

The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.


Background

Interleukin-2 (IL2) is a key cytokine that plays a crucial role in the immune system, particularly in the activation and regulation of immune responses. First discovered in 1976, IL-2 was initially referred to as "T-cell growth factor" due to its role in the proliferation of T cells, a vital component of the immune system. IL-2 has since become recognized as one of the most important cytokines for maintaining immune homeostasis and enhancing the activity of immune cells, including natural killer (NK) cells, B cells, and T cells. Its role in immune modulation has significant implications in both health and disease, including cancer, autoimmune diseases, and infections.

Características del producto

category

Primary Antibodies


clonality

polyclonal


reactivity

human


immunogen target

interleukin 2


host

Rabbit


isotype

IgG


conjugation

Unconjugated


form

liquid


tested applications

ELISA, WB, IHC


observerd MW

22 kDa


purity

≥95% as determined by SDS-PAGE


purification

Immunogen affinity purified


recommended dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:100


size 1

100µg


storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)


or code

IL2


alias

IL-2,TCGF,lymphokine,T-cell growth factor


note

This product is for research use only.


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