anti- IL10RB antibody

Descripción

Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes(ISG), which contribute to the antiviral state.

Características del producto

clonality

polyclonal

reactivity

human,mouse

immunogen target

interleukin 10 receptor, beta

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

liquid

tested applications

ELISA, WB

observerd MW

42-45 kDa

purity

≥95% as determined by SDS-PAGE

purification

Immunogen affinity purified

recommended dilution

WB: 1:500-1:2000

size 1

100µg

storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

or code

IL10RB

alias

CRFB4,Cytokine receptor family 2 member 4,CRF2-4,Interleukin-10 receptor subunit 2,IL-10R subunit 2,IL-10R2

uniprot id

https://www.uniprot.org/uniprotkb/Q08334

gene id

https://www.ncbi.nlm.nih.gov/gene/3588

note

This product is for research use only.

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Human IL10Rβ(Interleukin 10 Receptor Beta) ELISA Kit

proveedor

FineTest

reference

EH3264

reactivity

human

status

RUO

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