The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.
Primary Antibodies
polyclonal
human,mouse,rat
interleukin 10 receptor, alpha
Rabbit
IgG
Unconjugated
liquid
ELISA, WB, IHC, IF
72 kDa
≥95% as determined by SDS-PAGE
Immunogen affinity purified
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
100µg
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
IL10RA
CD210,Interleukin-10 receptor subunit 1,IL-10R subunit 1,IL-10R1)
This product is for research use only.
The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon re...
Precio a consultar
Ver másIL10RA Antibody is a Rabbit Polyclonal antibody against IL10RA. The protein encoded by this gene is a receptor for inter...
175€ (20 µl)
Ver másIL10RA is a receptor for IL10; binds IL10 with a high affinity.
281.25€ (80 µl)
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