IL24 antibody

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935106861
info@markelab.com
name
IL24 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04257
tested applications
ELISA, WB
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | interleukin 24 (IL24) |
Host | Rabbit |
Reactivity | Human, Mouse |
Recommended Dilution | WB: 1:500-1:2000 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | Q13007 |
Alias | C49A,FISP,MDA7,MOB5,ST16,IL10B,Melanoma differentiation-associated gene 7 protein,Suppression of tumorigenicity 16 protein |
Background | Antibody anti-IL24 |
Status | RUO |
Note | Mol. Weight 24 kDa |
Interleukin 24 (IL24) is a cytokine belonging to the IL-10 family, which includes other related cytokines such as IL-10, IL-19, IL-20, IL-22, and IL-26. IL-24 was first identified as melanoma differentiation-associated gene-7 (mda-7), due to its expression being upregulated during the process of melanoma cell differentiation. It plays a key role in immune regulation, cell survival, apoptosis, and the modulation of inflammatory responses. IL-24 is unique in its ability to induce apoptosis selectively in cancer cells without affecting normal cells, making it a promising therapeutic target for cancer treatment. IL-24 is produced by a variety of immune cells, including macrophages, monocytes, and T-cells, and is involved in both immune modulation and inflammation. Its expression can be triggered by pro-inflammatory signals, such as TNF-α and IFN-γ
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